A database of hormones and their receptors

Receptor

Search Result - 1

HMRbase accession number	20068
Swiss-prot Accession number	Q8SQ54 (Sequence in FASTA format)
Description	Melanin-concentrating hormone receptor 2 (MCH receptor 2) (MCHR-2)(MCH-R2) (MCH2R) (MCH-2R) (MCH2) (G-protein coupled receptor 145)(GPRv17).
Source organism	Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis.
Protein Length	340 Amino acids
Molecular weight	38770
Domain Name	7tm_1
References	1 Kurama T., Matsumoto S., Takasaki J., Terai K., Matsumoto M.,Kamohara M., Saito T., Soga T., Saito Y., Oda T., Masuho Y.,Furuichi K.; "Molecular characterization of a novel melanin-concentrating hormonereceptor: evidence of its expression in lateral hypothalamus."; Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 2

HMRbase accession number	20431
Swiss-prot Accession number	Q8HXX3 (Sequence in FASTA format)
Description	Melanocortin receptor 4 (MC4-R).
Source organism	Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity).
Protein Length	332 Amino acids
Molecular weight	37002
Domain Name	7tm_1
References	1 Kusuda J., Osada N., Hida M., Sugano S., Hashimoto K.; "Isolation and characterization of cDNA for macaque neurologicaldisease genes."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 3

HMRbase accession number	21023
Swiss-prot Accession number	P32212 (Sequence in FASTA format)
Description	Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor).
Source organism	Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats.
Tissue Specificity	N/A
Post translational modification	N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity).
Function	Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Protein Length	695 Amino acids
Molecular weight	78245
Domain Name	N/A
References	1 PubMed abstract 7504463 2 Gromoll J.; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 7504463 4 Gromoll J.; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
Hormone	Q6EV79 Detail in HMRbase Q9BEH3 Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 4

HMRbase accession number	21211
Swiss-prot Accession number	O97952 (Sequence in FASTA format)
Description	RecName: Androgen receptor;Alternative Name: Dihydrotestosterone receptor;Alternative Name: Nuclear receptor subfamily 3 group C member 4;
Source organism	Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular location	Nucleus (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	Phosphorylated in prostate cancer cells in response to several growth factors including EGF. Phosphorylation is induced by c-Src kinase (CSK). Tyr-510 is one of the major phosphorylation sites and an increase in phosphorylation and Src kinase activity is associated with prostate cancer progression (By similarity).
Function	Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 (By similarity).
Protein Length	895 Amino acids
Molecular weight	96495
Domain Name	Androgen_recep Hormone_recep zf-C4
References	1 PubMed abstract 9732460
Hormone	Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 5

HMRbase accession number	21553
Swiss-prot Accession number	Q4R5Y1 (Sequence in FASTA format)
Description	Testis cDNA, clone: QtsA-19884, similar to human nuclear receptor subfamily 1, group I, member 2 (NR1I2),transcript variant 1,
Source organism	Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	342 Amino acids
Molecular weight	39150
Domain Name	Hormone_recep zf-C4
References	1 PubMed abstract 15944441
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 6

HMRbase accession number	22466
Swiss-prot Accession number	Q8MHZ0 (Sequence in FASTA format)
Description	Peroxisome proliferator-activated receptor gamma 4;Peroxisome proliferator-activated receptor gamma 6
Source organism	Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	483 Amino acids
Molecular weight	55365
Domain Name	Hormone_recep zf-C4
References	1 PubMed abstract 12054596
Hormone	Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 7

HMRbase accession number	22626
Swiss-prot Accession number	Q95J17 (Sequence in FASTA format)
Description	Peroxisome proliferator-activated receptor gamma 1;Peroxisome proliferator-activated receptor gamma 5;Peroxisome proliferator-activated receptor gamma 7;Peroxisome proliferator-activated receptor gamma 3
Source organism	Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	475 Amino acids
Molecular weight	54471
Domain Name	Hormone_recep zf-C4
References	1 PubMed abstract 12054596
Hormone	Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 8

HMRbase accession number	22631
Swiss-prot Accession number	Q95K90 (Sequence in FASTA format)
Description	Putative uncharacterized protein
Source organism	Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	603 Amino acids
Molecular weight	67256
Domain Name	Hormone_recep zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 9

HMRbase accession number	22633
Swiss-prot Accession number	Q95KZ8 (Sequence in FASTA format)
Description	Peroxisome proliferator-activated receptor gamma 2
Source organism	Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	505 Amino acids
Molecular weight	57624
Domain Name	Hormone_recep zf-C4
References	1 PubMed abstract 12054596
Hormone	Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments